Tuesday, 19 January 2010

Biomedical engineering


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Biomedical engineering (BME) is the application of engineering principles and techniques to the medical field. It combines the design and problem solving skills of engineering with medical and biological sciences to help improve patient health care and the quality of life of individuals.

As a relatively new discipline, much of the work in biomedical engineering consists of research and development, covering an array of fields: bioinformatics, medical imaging, image processing, physiological signal processing, biomechanics, biomaterials and bioengineering, systems analysis, 3-D modeling, etc. Examples of concrete applications of biomedical engineering are the development and manufacture of biocompatible prostheses, medical devices, diagnostic devices and imaging equipment such as MRIs and EEGs, and pharmaceutical drugs.
Disciplines in biomedical engineering

Biomedical engineering is an interdisciplinary field, influenced by various fields and sources. Due to the extreme diversity, it is typical for a biomedical engineer to focus on a particular emphasis within this field. There are many different taxonomic breakdowns of BME, one such listing defines the aspects of the field as such

Bioelectrical and neural engineering
Biomedical imaging and biomedical optics
Biomaterials
Biomechanics and biotransport
Biomedical devices and instrumentation
Molecular, cellular and tissue engineering
Systems and integrative engineering
In other cases, disciplines within BME are broken down based on the closest association to another, more established engineering field, which typically include:

- Chemical engineering - often associated with biochemical, cellular, molecular and tissue engineering, biomaterials, and biotransport.
- Electrical engineering - often associated with bioelectrical and neural engineering, bioinstrumentation, biomedical imaging, and medical devices.
- Mechanical engineering - often associated with biomechanics, biotransport, medical devices, and modeling of biological systems.
- Optics and Optical engineering - biomedical optics, imaging and medical devices.

Medical devices can be regulated and classified (in the US) as shown below:

Class I devices present minimal potential for harm to the user and are often simpler in design than Class II or Class III devices. Devices in this category include tongue depressors, bedpans, elastic bandages, examination gloves, and hand-held surgical instruments and other similar types of common equipment.
Class II devices are subject to special controls in addition to the general controls of Class I devices. Special controls may include special labeling requirements, mandatory performance standards, and postmarket surveillance. Devices in this class are typically non-invasive and include x-ray machines, PACS, powered wheelchairs, infusion pumps, and surgical drapes.
Class III devices require premarket approval, a scientific review to ensure the device's safety and effectiveness, in addition to the general controls of Class I. Examples include replacement heart valves, silicone gel-filled breast implants, implanted cerebellar stimulators, implantable pacemaker pulse generators and endosseous (intra-bone) implants.

-- An MRI scan of a human head, an example of a biomedical engineering application of electrical engineering to diagnostic imaging. Click here to view an animated sequence of slices.Imaging technologies are often essential to medical diagnosis, and are typically the most complex equipment found in a hospital including:

Fluoroscopy
Magnetic resonance imaging (MRI)
Nuclear Medicine
Positron Emission Tomography (PET) PET scansPET-CT scans
Projection Radiography such as X-rays and CT scans
Tomography
Ultrasound
Electron Microscopy

-- Tissue engineering
One of the goals of tissue engineering is to create artificial organs for patients that need organ transplants. Biomedical engineers are currently researching methods of creating such organs. In one case bladders have been grown in lab and transplanted successfully into patients. Bioartificial organs, which utilize both synthetic and biological components, are also a focus area in research, such as with hepatic assist devices that utilize liver cells within an artificial bioreactor construct.

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