Covers proteins, carbohydrates, and genetics Grasp biochem basics, apply the science, and ace your exams Are you baffled by biochemistry? This unintimidating guide makes it easy to understand, explaining all the topics and practical applications in plain English. From cell ultrastructure and carbohydrates to amino acids, proteins, and supramolecular structure, you'll identify biochemical structures and reactions, improve your grades, and get ready to tackle your tests. John Moore, EdD, is the author of Chemistry For Dummies and an editor for The Journal of Chemical Education. Richard Langley, PhD, is a grader for the Free Response
Thursday, 30 October 2008
Biochemistry For Dummies
Viral Therapy of Cancer
Viral agents have been developed that are harmless to normal tissues but selectively able to kill cancer cells. These agents have been endowed with additional selectivity and potency through genetic manipulation. Increasingly these viruses are undergoing evaluation in clinical trials, both as single agents and in combination with standard chemotherapy and radiotherapy. This book provides a comprehensive yet succinct overview of the current status of viral therapy of cancer. Chapters coherently present the advances made with individual agents and review the biological and clinical background to a range of viral therapies: structured to proceed from basic science at the bench to the patient’s bedside, they give an up-to-date and realistic evaluation of a therapy’s potential utility for the cancer patient. * Presents state of the art knowledge on how viruses can be, and have been, used in novel therapeutic app
roaches for the treatment of cancer * Describes the use of viruses as oncolytic agents, killing cells directly * Editors are experts in the field, with experience of both laboratory and clinical research Viral Therapy of Cancer is essential reading for both basic scientists and clinicians with an interest in viral therapy and gene therapy
Digestion and Nutrition
Autoantibodies
Autoimmune diseases are characterized by the occurrence of antibodies reacting with self constituents of the body. This exciting new reference is an exhaustive review of the main autoantibodies identified up to now, with particular emphasis on those autoantibodies that display a clinical value. Each chapter is focussed on a single family of autoantibodies by reviewing their historical notes, definition, origin and source(s) of the antigen(s) recognized, genetic associations, pathogenic mechanisms that are mediated, method(s) of detection and clinical utility (disease prevalence/associati
on, diagnostic value, sensitivity and specificity, prognostic value). An ideal reference for anyone involved in the field of autoimmune diseases. * Incudes and exhaustive list of autoantibodies not covered by other publications * Short reviews can easyily be checked for quick reference information * Both basic and clinical aspects are covered
Monday, 13 October 2008
Bioinorganic Electrochemistry
Interfacial electrochemistry of redox metalloproteins and DNA-based molecules is presently moving towards new levels of structural and functional resolution. This is the result of powerful interdisciplinary efforts. Underlying fundamentals of biological electron and proton transfer is increasingly well understood although with outstanding unresolved issues. Comprehensive bioelectrochemical studies have mapped the working environments for bioelectrochemical electron transfer, supported by the availability of mutant proteins and other powerful biotechnology. Introduction of surface spectroscopy, the scanning probe microscopies, and other solid state and surface physics methodology has finally offered exciting new fundamental and technological openings in interfacial bioelectrochemistry of both redox proteins and DNA-based molecules. Inorganic Bioelectrochemistry provides a thorough and didactic overview of state-of-the-art bioelectrochemistry with prospects for forthcoming development. The book is organized in eight chapters written by leading international experts and covers crucial relevant topics such as electron and proton transfer in metalloprotein systems, electrochemistry and electrocatalysis of redox enzymes, and electrochemistry of DNA-based molecules. A wide variety of readers will find this volume of great interest. These include final year underg
raduate and postgraduate students, university lecturers in inorganic and physical chemistry as well as the biochemical and biological sciences, and research staff in medical and biotechnological companies, catalysis research, and other industries.
Genetics of Developmental Disabilities
This authoritative reference provides expert discussions of the development, classification, diagnosis, and treatment of developmental disabilities-emphasizing research advances in genetics, molecular and cytogenetic testing, and molecular biological technologies for an improved understanding of the causes and factors that may contribute to these disorder
s.
RNAi
Title: RNAi: RNAi (Advanced Methods)
Author(s): Mart Latterich
Series: n/a
Publisher: Taylor & Francis
ISBN: 0415409500
Pages: 138.Medical Biotechnology
Wednesday, 8 October 2008
2 October 2008 - Nature Issue
Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surTuesday, 7 October 2008
Nucleic Acids in Innate Immunity
Until recently, innate immunity was regarded as a relatively nonspecific system designed to engulf and destroy pathogens. However, new studies show that the innate immune system is highly developed in its ability to discriminate between self and foreign entities. Understanding this mechanism can lead to therapeutic strategies based on manipulation of this previously unexploited branch of the immune system. Drawing on the research of leading experts, Nucleic Acids in Innate Immunity provides insight in this new area of immunology. The book begins by explaining the roles of nucleic acids in immunity, describing the mechanism of discrimination based on pattern-recognition receptors (PRRs), including Toll-like receptors (TLRs), Nod-like receptors (NLR), and RIG-I-like receptors (RLR). RNA are recognized by the innate immune system. Contributions
Bioprocessing-Biotechnology
Bioprocessing: an exciting new engineering discipline. It combines the development and optimization of biotechnological processes with effective strategies to recover and purify the desired products. Safety as well as cost play an important role here. This volume covers the immensely differentiated spectrum of techniques and operations of bioprocessing, presented by the most competent experts in the field. An overview of upstream and downstream processing is given, fermentation and cell culture processes and the design of microbial fermenters are presented. A closing
group of chapters is dedicated to issues of process validation, measurement, and regulation. Topics included are: Industrial Cell Cultures/ Pharmaceutical Proteins/ Bioreactors/ Media and Air Sterilization/ Oxygen Transfer/ Scale Implications/ Fermentation Data Analysis/ Cell and Debris Removal/ Protein Purification/ Electrokinetic Separations/ Final Recovery Steps/ Process Validations.
Phagocytosis of Bacteria and Bacterial Pathogenicity
Sunday, 5 October 2008
Instant Notes in Biochemistry
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Introduction to Pharmacology
The first edition of Introduction to Pharmacology has over recent years become a highly influential text among students wishing to acquire a knowledge of pharmacology without having to refer to the larger, more detailed, traditional pharmacology volumes. This revised and updated second edition contains significant new material to bring the reader up-to-date with the latest practices and principles in pharmacology. Exploring the basic principles in both the therapeutic and toxicological aspects of drug use, the book employs contemporary examples of medication, supplemented with an increased number of accurate and easy-to-interpret figures and diagrams. Additionally, Introduction to Pharmacology presents the important concept of understanding the limitations surrounding the drugs that cure, replace physiological inadequacies, or treat sympt
oms, and which have led to the system of drug classification. The broad scope of the book also encompasses the role of the FDA, drugs in sport, and the use of animals for drug experimentation.
Structural Proteomics: High-Throughput Methods
Structural genomics is a newly emerging field that has arisen following the successful footsteps of the major sequencing efforts generally bundled under the heading "genomics". In Structural Proteomics: High Throughput Methods, readers are provided with a current view of all aspects of the 'pipeline' that takes protein targets to structures and how these have been optimized. This volume includes chapters describing in-depth the individual steps in the Structural Genomics pipeline, as well as overviews of individual Structural Genomics initiatives. Topics include Target Selection for structural genomics, Protein structure modeling, High-throughput cloning, Mass Spectrometry modeling. Structural Proteomics: High Throughput Methods, encourages its readers to access further details on the methodologies in on-line resources as well as in cited literature making it an invaluable resource. Most methods in this important book are as amenable to small labo
ratories as to large consortia, and do not require major investments in facilities. This essential volume provides insight into the diversity of approaches adopted by different laboratories and proves that 'high throughput' is really the defining characteristic.
Thursday, 2 October 2008
DNA: Promise and Peril
The genetic revolution has provided incredibly valuable information about our DNA, information that can be used to benefit and inform--but also to judge, discriminate, and abuse. An essential reference for living in today's world, this book gives the background information critical to understanding how genetics is now affecting our everyday lives. Written in clear, lively language, it gives a compr
ehensive view of exciting recent discoveries and explores the ethical, legal, and social issues that have arisen with each new development.
Dendritic Cell Interactions with Bacteria
Emerging evidence suggests that dendritic cells play a major role in the orchestration of the immune response to bacteria. This volume introduces the reader to the complex world of dendritic cells and describes how the intimate interplay between dendritic cells, bacteria and the environment dictates either the induction of immunity or tolerance to the encountered microorganisms. It discusses how this can allow organisms to tolerate beneficial bacteria and to react against pathogens, as well as the strategies pathogenic bacteria have evolved to escape dendritic cell patrolling. Expert contributors discuss everything from bacterial capture and recognition to their killing, processing and the induction of ada
Aquaculture Engineering
Aquaculture engineering requires knowledge of the many general aspects of engineering such as material technology, building design and construction, mechanical engineering and environmental engineering. In this comprehensive book, Odd-Ivar Lekang introduces these principles and demonstrates how such technical knowledge can be applied to aquaculture systems, offering the reader coverage including: • Construction and design of aquatic production facilities • Water tra
Introduction to Fungi
This new edition of the universally acclaimed textbook on fungal biology has been completely re-written, to take account of recent progress in the taxonomy, cell and molecular biology, biochemistry, pathology and ecology of the fungi. Features of taxonomic relevance are integrated with natural functions, including their relevance to human affairs. Special emphasis is placed on the biology and control of human and plant pathogens, providing a vital link between fundamental and applied mycology. The emphasis throughout is on whole-organism biology from an integrated, multidisciplinary perspective. ![]()